Such versatility has established coumarins as a prominent focus in modern medicinal chemistry ... targeting proteins such as carbonic anhydrase and tubulin. These advances not only contribute ...

Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata, La Plata, Buenos Aires ...

Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Monastir 5000, ...

A research team has developed a new class of compounds that effectively inhibit both wild-type CDK9 and its drug-resistant ...

After the administration of a single dose of the drug to this patient, the urine was examined for carbonic anhydrase inhibitor activity. Seventy-two per cent of the administered drug was recovered ...

The ACSMEDI-EFMC Medicinal Chemistry Frontiers is co-organized by ACS MEDI (Division of Medicinal Chemistry of the American Chemical Society), and EFMC (European Federation for Medicinal chemistry and ...

Int Ophthalmol Clin. 2014;54(1):103-114. Topiramate is typically started at 25 mg daily and can be titrated up to 100 mg twice daily. It is frequently given in addition to acetazolamide in the ...

Since its approval in 1999, Vioxx, a selective cyclooxygenase-2 (COX-2) inhibitor, has been Merck & Co’s leading drug for control of acute pain and chronic pain associated with osteoarthritis, ...