The recommended target dose is 10 mg twice daily. The US FDA recently approved an extended-release (ER) formulation of memantine for once-daily 28-mg dosing. Memantine ER was evaluated in a 24 ...

Memantine HCl 7mg, 14mg, 21mg, 28mg; ext-rel caps. Tabs—60; Titration Pak (28 x 5mg + 21 x 10mg)—1; Oral soln—contact supplier; XR caps 7mg, 21mg—30; 14mg, 28mg—30, 90; XR Titration Pak ...

(mean 6.3); 82 patients were randomized to memantine (10 mg/day) and 84 were randomized to placebo. Overall outcomes significantly favored the treatment group on measures of global assessment and ...