Researchers have identified the mitochondrial calcium uniporter as a critical protein in the strengthening of synaptic ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...