C&EN20d
Synergistic Enhancement of Ferroptosis via Mitochondrial Accumulation and Photodynamic-Controlled Release of an Organogold(I) Cluster Prodrug
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...
eLife28d
B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...
Frontiers1mon
Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis
To observe the morphological changes associated with mitochondrial ferroptosis in breast cancer cells, the following transmission electron microscopy (TEM) procedure was employed: cell fixation, ...
C&EN1mon
Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
From the GO analysis, we screened the upregulated differentially expressed genes and identified key pathways, including mitophagy, autophagy, ferroptosis ... fluorescence microscope (Axio Observer 3, ...
Hosted on MSN1mon
Wasp inside an Electron Microscope
Breaking Taps Wasp inside an Electron Microscope Posted: January 10, 2025 | Last updated: January 10, 2025 Common Hoverfly Parasitoid Wasps! Today we're looking at a wasp I found in my backyard ...
New Scientist1mon
World’s first fully 3D-printed microscope made in under 3 hours
The world’s first fully 3D-printed microscope can be made in a few hours and for a fraction of the cost of traditional ones. “It’s not just enabling, it’s empowering,” says Gail ...
Frontiers1mon
The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation
Furthermore, low expression of PCBP1 promoted ferroptosis by increasing the ... were imaged and counted under an Olympus FSX100 microscope. Mitochondrial morphology was observed using transmission ...
eLife2mon
PEBP1 amplifies mitochondrial dysfunction induced integrated stress response
In this article, Cheng et al present an important finding that advances the understanding of mitochondrial stress response(s). The authors employed mass spectrometry-based methods in conjunction with ...
CERN2y
The Large Electron-Positron Collider
LEP – the largest electron-positron accelerator ever built – was dismantled in 2000. Its 27-kilometre tunnel now hosts the LHC With its 27-kilometre circumference, the Large Electron-Positron (LEP) ...
Fred Hutch3y
Electron Microscopy
The Electron Microscopy shared resource offers techniques that allow researchers to resolve structures from cellular ultrastructure all the way down to molecular interactions. Our expertise in EM ...