Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...
A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...
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Mitochondrial study offers new insights into how our cells process RNA for energy productionOne key finding is the discovery of the 5′-to-3′ processing order ... Structural basis of 3′-tRNA maturation by the human mitochondrial RNase Z complex, The EMBO Journal (2024).
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...
Analogous to chromosomal DNA that wraps around histone proteins to fit in the nucleus, mtDNA molecules are compacted into mtDNA-protein complexes termed nucleoids. Mitochondrial nucleoid proteins ...
Our lab studies the structure and function of mitochondrial membrane-shaping protein complexes in human parasites, and the bioenergetic role of mitochondrial energy-converting complexes in human ...
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