Recent years have seen considerable advances in the description and understanding of mitochondrial DNA (mtDNA) disorders. However, progress towards therapies and prenatal diagnosis of mtDNA ...

The mitochondrial genome is the full genetic complement of a mitochondrion. Mitochondrial DNA is only a small portion of the total DNA of a eukaryotic cell and in most species is solely inherited ...

We now show that NT induces release of extracellular mitochondrial DNA (mtDNA) that could act as "autoimmune" trigger. We further show that serum from young autistic patients contains mtDNA (n ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...