Monogenic hypertension is caused by single gene mutations ... which suppresses plasma renin activity These disorders should be suspected in young patients with a familyhistory of hypertension ...
We believe, and have now demonstrated, that gene therapy is a rational approach for the treatment of rare monogenic diseases ... candidates for SMA, Rett syndrome, SOD1 amyotrophic lateral ...
Liddle syndrome is an autosomal dominant disorder ... Competing Interests: The authors declared no competing interests. Monogenic hypertension is caused by single gene mutations and accounts ...