We showed that conversion of Aβ to the fibrillar form markedly increased binding to specific neuronal membrane proteins, including amyloid precursor protein (APP). Nanomolar concentrations of ...

Thirst is a crucial physiological signal that contributes to the survival of humans and other animals, by allowing them to ...

Falls account for two-thirds of TBIs in adults over 65.  Preventing falls is therefore key to mitigating the risk of TBI.

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

Abstract: Goal: Activities of neuronal networks range from action potential firing of individual neurons, coordinated oscillations of local neuronal assemblies, and distributed neural populations.

The complex interactions between the nervous and immune systems are pivotal in both health and disease, but the cellular and molecular mechanisms underlying ...

Aromatic Scents, Essential Oils, Fragrance Toxicity, Fragrance Compounds, Aromatic Exposure, Neurotoxicity, Respiratory ...

Scientists at UCL Institute of Neurology have discovered how certain forms of motor neuron disease begin and progress at cellular and molecular levels, revealing potential new ways to slow down or ...