For example, a UK study by Dixon et al. 9 compared the risk of tuberculosis ... K., Solomon, D. & Kim, S. Active-comparator design and new-user design in observational studies ...

Why register observational studies? Much of the rationale for the prospective registration of clinical trials 9 applies to the registration of observational studies (). 7 For example, observational ...

Incorporating the patient experience into observational studies can enhance the quality of real-world evidence gathered. Learn how patient-centred approaches can lead to stronger research outcomes.

“This large observational study looked at health records of over 26,000 people in the US diagnosed with chronic lower back pain and who were prescribed gabapentin within a 10-year period. They found ...

Why with observation alone there is no random assignment of exposure, so confounding by other factors should always be considered as an explanation for associations found in an observational study.

The repetition of the “only an observational study” mantra ignores the fact that randomised studies are often impossible - for example, if we want to study the impact of genes, long-term ...

Familiarity with notions of research design in the social sciences, to the level ... difference-in-difference, and regression discontinuity. Examples are drawn from different social sciences. The ...

The study results should not be taken to rule out either benefit or harm of hydroxychloroquine treatment, given the observational design and the 95% confidence interval, but the results do not ...

Why with observation alone there is no random assignment of exposure, so confounding by other factors should always be considered as an explanation for associations found in an observational study.