Rotating to another opioid may be helpful, as cross-tolerance is not universal. [15] If this is not effective, then it may be necessary to focus instead on the patient's functional status and ...

As with climate change, why are we so slow to recognise the existential threat that drug use poses to humanity?

On a day dedicated to fighting cancer, the fentanyl crisis turned medicine into a battleground, igniting a US-China tariff war ...

Opioid dose increases at the EOL for PWUD are of similar ... by PWUD to manage comorbid conditions and to alleviate drug craving, with the potential for cross-tolerance to develop.14 15 Existing ...

We are in an era of unprecedented tolerance and perceived legitimacy of psychedelics ... Among the key questions: Given the quality of extant research including cross-sectional designs, reliance on ...

It may take time for the body to respond to CBD and build a tolerance. Consistently taking ... That said, a 2022 cross-sectional study on CBD use reported improvements in pain (83%), physical ...

Hence Trump’s old-fashionedness: his need for rallies and town halls, his belief in the importance of crowd sizes, his dance to the music (that gift to the comics), his tolerance of ... at the gas ...

Start with half a gummy to assess your THC tolerance, and increase the dose gradually if needed ... That being said, CBD may interact with anti-epileptic drugs, antidepressants, and opioids. Safety ...

A recent study explodes the myth that the risk of addiction to prescription opioids exists only among patients abusing their opioids. Until recently, the National Survey on Drug Use and Health ...

The percentage of patients receiving medication for opioid use disorder in federally qualified health centers increased from 2017 to 2023.

Unlike opium, nitazenes and other synthetic opioids can be produced anywhere in the world using precursor chemicals that are often uncontrolled.