Optimal therapeutic targeting of cancer involves clonal signals which are expressed within all cancer cellsGradalis applies a novel clinically ...

Seven PBMC samples were partitioned and sequenced that produced 28,810 single cell transcriptomes distributed across 36 clusters and classified into 13 general cell types including plasmacytoid ...

Migration of neutrophils, isolated from PBMC of HDs by magnetic beads (EasyStep enrichment ... limited numbers and did not include significant fractions of IL-17+ cells (figure 2A, B). Evaluation of ...

Activation of nuclear factor kappa B (NFκB), which is involved in their gene transcription ... isolated lamina propria cells (LPMC), and peripheral blood mononuclear cells (PBMC) were cultured with or ...

DNA was isolated from tissue and PBMC (Qiagen Tissue DNA Kit ... T cells hold a dominant position, and the proportion of granulocytes, epithelial cells, macrophages, and plasma B cells was comparable, ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...

Wojciech Jurczak, MD, PhD, ​​discusses the future of B-cell lymphoma therapy, with a focus on Bruton's tyrosine kinase ...

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...