Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better understand the molecular mechanisms behind these sensations of heat and pain.

Functions of Aβ-LTMRs in chronic pain have been of great interest but are controversial. On one hand, several studies suggested that Aβ-LTMRs may mediate mechanical hyperalgesia of chronic pain ...

Scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications.

"Delta receptors are located throughout the body on pathways and neurons that transmit pain signals to the brain," said Jay McLaughlin, Ph.D., a professor of pharmacodynamics in the UF College of ...

on the other hand, inhibit the sensitivity to other noxious chemical stimuli." To alleviate pain, previous potential ...