Malaria remains a major global healthcare burden, responsible for hundreds of thousands of deaths annually. The complexity of ...

One of the biggest threats to human health and to both animal and plant production is infection by antibiotic resistant ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading ...

New research shows that harmful E. coli bacteria in the gut can make the amoeba parasite Entamoeba histolytica more mobile ...

1). Effective phagocytosis therefore requires two components: particle internalization and phagosomal maturation. Although most bacteria are successfully internalized and eliminated by phagocytes ...

Edited* by Xiaodong Wang, University of Texas Southwestern Medical Center, Dallas, TX, and approved September 7, 2010 (received for review June 24, 2010) ...

Phagocytosis is triggered after ligation of cell-surface receptors. Similar to mammals, D. melanogaster uses multiple mechanisms of bacterial recognition, such as complement-like opsonization and ...

Get Instant Summarized Text (Gist) A host protein, APOL9, selectively binds to Bacteroidales bacteria in the gut by recognizing their unique lipid, ceramide-1-phosphate (Cer1P). This interaction ...

The human gut is home to trillions of microbes that not only aid in digestion but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range ...

Researchers shed light on the "dark matter" of the gut, revealing a species of fungus that could potentially help counter fatty liver disease. The research is in its early days, though.