Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark ...

Pregnenolone is a steroid hormone that naturally exists in our bodies and is instrumental in creating other hormones including estrogen, testosterone, and cortisol. With advancing age, the levels ...

Fluvoxamine (flv, 5 and 10 mg/kg, in saline) and diazepam (diaz, 1.25 and 5 mg/kg, in 0.3% propylene glycol, 0.06% ethanol) were purchased from Sigma-Aldrich Inc., and administered in a volume of 10 ...

Mitochondrial dysfunction has been recognized as a key player in neurodegenerative diseases, including Alzheimer's disease (AD) and Niemann–Pick type C (NPC) disease. While the pathogenesis of both ...