The walkaway nature of the agarose gel electrophoresis systems provides ... compact electrophoresis systems with a throughput of 162 proteins, 45 hemoglobins or 18 immunofixations in just one ...

Michael Lämmerhofer from the Institute of Pharmaceutical Sciences, University of Tübingen, Germany, spoke to JFK Huber ...

To identify covalent AKR1C3 inhibitors, we screened compounds in live cells and evaluated the following parameters: (i) covalency via an RJG-2121-mediated competitive activity-based protein profiling ...

Bacterial cells were subsequently centrifuged and lysed by sonication, and the recombinant protein was purified using Ni-NTA Beads 6FF Agarose (Solarbio ... was used for stain-free gel visualization.

Gel electrophoresis is a staple of many life science labs but has changed little since the 20th century. Now, researchers ...

The E-Gel ® electrophoresis system is ideal for routine analysis of PCR products, restriction digests, and plasmid preparations. No gels to pour, no buffer to make, no staining/destaining ...

Here, we expand the repertoire of PROTAC compatible E3 ligases by identifying a novel small molecule scaffold targeting the ubiquitin E3 ligase KLHDC2 using a fluorescence polarization-based high ...

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...