In a new discovery, chronic pain has been shown to be physiologically different from acute pain and now scientists have the ...

I Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of ...

namely GPCR kinases and second message kinases (such as protein kinase A and protein kinase C) (Lefkowitz, 1998). A large number of GPCR phosphorylation sites have been reported, mostly using mass ...

Meiotic errors in oocytes cause egg aneuploidy. This study shows that kinetochores employ MPS1 kinase to promote timely ...

Insilico plans late-stage trials for rentosertib following positive mid-stage safety and efficacy data for idiopathic ...

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

Find more information on the Altmetric Attention Score and how the score is calculated. Protein kinase C-α (PKCα) has been studied widely as a paradigm for conventional PKCs, with two C1 domains (C1A ...

The antimitotic properties of parthenolide, a natural compound with known anticancer activity, have been largely ...

Protein kinase C (PKC) is a family of serine/threonine kinases ... in many cell types through increased activation of the Akt pathway and upregulation of pro-survival factors.

Macrophage-inducible C-type lectin (Mincle, CLEC4E ... This study was designed to investigate the role of Mincle and its downstream spleen tyrosine kinase (Syk) signal pathway in early brain injury ...

CHICAGO -- Adding the PI3K-pathway inhibitor ... "We've been trying to develop PI3 kinase inhibitors for many years and what ...