ROR1 is a cellular protein normally found in ... has been discontinued, along with CAR-T therapies from Lyell and Oncternal, on toxicity issues. DLBCL accounts for up to 30% of all NHL cases ...

PRGN-3007, a blood tumor and solid tumor candidate simultaneously expressing a CAR targeting receptor tyrosine kinase-like orphan receptor 1 (ROR1), mbIL15, a kill switch, and a novel mechanism ...

IM-1021 is an optimized, ROR1-targeted ADC that incorporates Immunome’s proprietary TOP1 inhibitor, HC74. The Phase 1 trial is an open-label, multicenter dose escalation and expansion study ...

Among sleek electric cars and futuristic tech at the 2025 Silicon Valley Auto Show, one vehicle stole the spotlight: the Alef Flying Car. Yes, it is a real-life flying car, not a CGI concept or an ...

The existing data underscore its broad potential in both lymphomas and solid tumors. Notably, a ROR1 ADC combined with R-CHP has demonstrated an impressive complete response (CR) rate in a Phase II ...

The average new car price in the U.S. was $48,641 in January, up 1.3% from the year before, according to Kelley Blue Book. Consumer Reports’ most recent top cars, trucks and SUVs list ...

The results of a phase 2 trial of MSD’s ROR1 inhibitor zilovertamab vedotin (zilo-V) back up the company's decision to push the antibody-drug conjugate (ADC) into a phase 3 programme.

We recently published the best nationwide incentives for models recommended by Consumer Reports, the best new-car deals, and the best new SUV deals. Those forward-looking articles show where ...

We found that when adding a 16-year-old driver to a parent’s policy, the average car insurance cost jumped from $2,603 per year to $5,011 per year. That’s an average increase of 103%.