Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

RT-qPCR validated a significant decrease in mRNA levels of BTC ... Identification of BTC and KLF15 in Vascular Smooth Muscle Cells as Key Biomarkers for Abdominal Aortic Aneurysm via Machine Learning ...

The digital PCR (dPCR) and real-time PCR (qPCR) market is set to witness a high growth rate of ~7% in the next 5 years. Increasing demand for accurate and sensitive molecular diagnostics, growing ...

Canadian scientists have developed a blood test and portable device that can determine the onset of sepsis faster and more ...

This important study provides evidence for asymptomatic Bordetella pertussis carriage among mothers in a longitudinal cohort in Zambia, significantly advancing understanding of transmission dynamics.

PCR-Machines are classified depending on the capacity of PCR used such as Nested PCR or Reverse Transcriptase PCR (RT-PCR ), or Multiplex RT PCR. PCR-machines are used for replication of DNA ...

For decades, machine-to-machine (M2M ... but the tools are better for legacy research and creation than real-time engagement. Generative AI excels at pattern recognition, synthesis, and expression ...

Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic candidates, like antibodies that bind to and fight the SARS-CoV-2 virus, can be ...