Figure 1: Targeted disruption of the mouse C3aR gene. Figure 3: Assessment of AHR to inhaled methacholine (MCh) in conscious mice. We immunized mice with 10 µg of OA and 1 mg of aluminium ...

Many patients with ER-positive/HER2-negative advanced breast cancer eventually develop resistance to standard first-line ...

Remarkably, the sequence of the cytoplasmic domain of the toll protein turned out to be similar to the cytoplasmic domain of the mammalian interleukin-1 receptor. 10 Moreover, both the interleukin ...

CHICAGO -- Combining pembrolizumab (Keytruda) with sacituzumab govitecan (SG, Trodelvy) instead of chemotherapy as first-line ...

In a promising new study, scientists have adapted an experimental cancer treatment to control celiac disease. The method ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

Local immune effector cell–associated toxicity syndrome is a newly identified side effect observed in many patients receiving CD19-targeting CAR T-cell therapy for autoimmune conditions.

and transforming growth factor-β (TGFβ), and they upregulate inhibitory receptors on effector T cells giving them an exhaustion phenotype. Many viruses infect humans and most are controlled ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...

Body cooling is death's reliable herald. Discover how this temperature decline occurs, what it reveals about our final hours, ...

During a live event, Naresh Bumma, MD, discussed CRS, oral and skin toxicities, and low discontinuation rates with ...