1132 G > C p.A378P substitution ... the genetic and biochemical changes would have been suggestive for the known clinical disease. To the best of our knowledge, this is the first report of ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...

In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan has used simulations on the Pittsburgh ...

Could a novel approach to genetic studies give us a clearer picture of how evolutionary adaptations occur? That's what the ...

In a novel theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Postdoctoral scholar Daniela Soto has earned a prestigious fellowship from HHMI with eight years of funding to study the ...

The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. .

The locus-specific mutation frequencies for copy number variation ... HR mechanisms generally achieve accurate repair of DNA damage. Double-stranded breaks are repaired by HR or by end-joining ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...