Missense mutations are genetic alterations arising from the substitution of a single base pair (bp) in an amino acid (aa) sequence with a different base pair, resulting in the translation of a ...

Among these eight SNPs, they found a missense mutation in PCSK9 that causes the amino acid substitution V474I ... analysis that established a gene signature linked to host PCSK9 inhibition ...

Discover why Exact Sciences, a leading oncology diagnostics company, may see growth in the cancer diagnostics market with its ...

The mutation—a substitution of a conserved proline residue ... High-frequency oscillations activate endosymbiotic gene expression, while low-frequency oscillations modulate phenylpropanoid ...

1132 G > C p.A378P substitution ... the genetic and biochemical changes would have been suggestive for the known clinical disease. To the best of our knowledge, this is the first report of ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...

A mutation that causes an amino-acid substitution in a channel called CNGC15 in the plant cell’s nucleus boosts the formation of such endosymbiotic relationships. Studying ion channels in their ...

Scientists at UC San Diego find that gene expression is linked to gene mutations and may be caused by them. That could make ...

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say. When you purchase through links on our site, we may earn an affiliate commission.

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to the Vanderbilt University Medical Center study ...