Even better, they discovered that lariocidin—named for its knotted, lasso-like chemical structure—has a unique mechanism of ...

He joined the faculty there as an assistant professor in 1946 and in 1948 began working on the synthesis of penicillin. The formation of a just small amount of natural penicillin from mold took months ...

The last time a new class of antibiotics reached the market was nearly three decades ago—but that could soon change, thanks ...

Enzymes, the core catalysts in life, drive critical biological processes ranging from metabolic regulation to energy ...

An efficient total-synthesis pathway with extraordinary flexibility ... against bacteria known to be resistant to tetracycline, penicillin, methicillin and/or vancomycin. These derivatives were ...

Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...

The beta-lactam ring portion of the antibiotic targets the penicillin-binding proteins (PBP), found in the bacterial cell membrane, which function in the synthesis of the cell wall. Binding of the ...