Roflumilast is a highly selective phosphodiesterase (PDE)-4 inhibitor with significant pulmonary and systemic anti-inflammatory effects. Roflumilast has a pharmacokinetic profile that permits once ...

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Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...

It was announced today that the weatherfront set to batter the UK on Friday, January 25, has been named Storm Éowyn. While most people will be concerned with the disruption it will cause, others ...

The integrative physiology of the left ventricle and systemic circulation is fundamental to our understanding of advanced heart failure and cardiogenic shock. In simplest terms, any increase in aortic ...

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As his career progressed, the actor gained a deeper understanding of the lasting effects of slavery through the systemic racism he says he faced over his 30-year journey in the industry.

This topical JAK inhibitor ointment ... combining high efficacy with minimal systemic exposure. Results from the 2024 Phase 2a trial showed efficacy comparable to biologics, outperforming current ...

Researchers from Aarhus University (AU) have developed a new technology that uses microorganisms to convert the CO2 in flue gas directly for new purposes—for example fuels or substances for the ...

Lisaftoclax is under clinical development by Ascentage Pharma Group International and currently in Phase II for Primary Systemic Amyloidosis ... The company specializes in designing inhibitors of ...

These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...