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Oxidized LDL-Induced Smooth Muscle Cell Proliferation Involves the EGF Receptor/PI-3 Kinase/Akt and the Sphingolipid Signaling Pathways
When indicated, SMCs were incubated with 100 μg apoB/mL oxLDL for 30 minutes (or EGF 10 nmol/L for 10 minutes) and 5 μmol/L AG1478. EGFR and associated proteins were coimmunoprecipitated and analyzed ...
C&EN17d
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5′-Adenosine Monophosphate-Activated Protein Kinase (AMPK)
Pfizer Worldwide Research and Development, 610 Main Street, Cambridge, Massachusetts 02139, United States ...
C&EN17d
Radicals Produced by γ-Irradiation of Hyperquenched Glassy Water Containing 2′-Deoxyguanosine-5′-monophosphate
Institute of Applied Radiation Chemistry, Technical University of Lodz, Wroblewskiego 15, 93-590 Lodz, Poland, and Institute of General, Inorganic and Theoretical Chemistry, Innsbruck University, ...
Beebom24d
iOS 18.5 Released: Here’s Everything New
After much waiting, Apple finally released iOS 18.5. It comes with some new additions and a couple of bug fixes. One of the most notable features bundled in the new iOS 18 update is the Satellite ...