Extraembryonic trophoblast lineages constitute the placenta, and are essential for individual development. In human early embryo development, these cells can be generated from totipotent blastomeres.

Conventional human pluripotent stem cells at the primed pluripotent state are capable of generating all the embryonic ...

Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University (L. Liu, Q.G., Y.C., S.C., L ...

pEVs stimulated the differentiation of trophoblast stem cells (TSCs) and enhanced the migration and invasion abilities of EVTs via CD147 receptor. Conversely, pEVs inhibited the tube formation ability ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

Pre-Market: 8:06:16 a.m. EST ...

The prevalence and mortality rates of cardiovascular diseases are increasing, and new treatment strategies are urgently needed. From the perspective of basic pathogenesis, the occurrence and ...

1 Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK 2 Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK Correspondence to Clare Teresa ...