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Bacterial Effector Alters Host Cell Death to Aid Infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis ...
Novel antibiotic BTZ-043 can also target TB bacteria hiding in dead lung tissue
Every year, 10 million people contract tuberculosis (TB), a disease caused by the bacterium Mycobacterium tuberculosis (Mtb), and approximately 1.5 million patients succumb to the disease. Treatment ...
High-speed microscopy reveals real-time protein translocation across a bacterial membrane
Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...
How Staphylococcus aureus 'steals' iron from our blood during infections
Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin—a process crucial to their survival ...
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Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Römpp, A., Treu, A., Kokesch-Himmelreich, J. et al. The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis. Nat Commun 16, ...