Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

An interdisciplinary research team from Leipzig University and the Saxon AI center ScaDS.AI has developed a novel approach ...

In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

C-terminal amidation is a PTM that involves the addition of an amid group to the C-terminus of a peptide or protein. Currently there is no direct evidence to suggest that C-terminal amidation of ...

(F) Sequence alignment of U-box domains in ... His-TEV-HsUbcH5a, His-TEV- (Tetra-ubiquitin) and His-Strep-TEV-HsUbiquitin the cell lysates over expressing the proteins were prepared as above. After ...

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and many toxins can chemically modify proteins across their entire sequence. How E3 ligases deal with such diverse substrates, especially those resulting from chemical insults, is still poorly ...

Department of Laboratory Medicine, Peking University Third Hospital, Beijing 100191, China Core Unit of National Clinical Research Center for Laboratory Medicine, Peking University Third Hospital, ...