We evaluated the safety and efficacy of larotrectinib in the cohort of pediatric patients with TRK fusion sarcomas and related mesenchymal tumors from two larotrectinib clinical trials: SCOUT and ...

inhibitor with efficacy in children with TRK fusion tumors. We evaluated patient outcomes after elective discontinuation of larotrectinib in the absence of disease progression in a protocol-defined ...

Research indicates that targeting the KCNB2 gene, associated with potassium channels, could improve treatments for medulloblastoma, a common malignant brain tumor in children. By inhibiting KCNB2 ...

In about 30 per cent of children with Wilms tumor, there is an inherited genetic change that increases the risk of developing this cancer. This study, published today (23 January) in Cancer ...

New research looked at how cancers arise in children who are predisposed to developing the childhood kidney cancer, Wilms tumor, which could help anticipate the development of tumors before they ...

In about 30% of children with Wilms tumor, there is an inherited genetic change that increases the risk of developing this cancer. A study, published 23 January in Cancer Discovery suggests that ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...