In a landmark discovery, researchers have unveiled the highly dynamic and adaptable architecture of the mammalian pyruvate ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

The publication of two potent ligands for the BET bromodomains in 2010 demonstrated that small molecules can inhibit the bromodomain–acetyl-lysine protein–protein ... Researchers at GSK also took a ...

Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. Please note: If you switch to a different device, you may be asked to login again with only ...