The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

NFL regular season reached its grand finale this Sunday with the full picture of the playoffs coming into focus. All 14 ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

Check out Kyler Murray's postgame interview after the Arizona Cardinals defeated the San Francisco 49ers in the last game of the regular season.

San Francisco 49ers FB Kyle Juszczyk hauled in a touchdown during the team's Week 18 matchup against the Cardinals.

The road ahead for the San Francisco 49ers in 2025 could be incredibly smooth. With the opponents they are set to face, they ...

Kyler Murray tied a career high with four touchdown passes and did not throw an interception Sunday to lead the Arizona ...

The Cardinals earned the No. 16 overall pick in the first round of the 2025 NFL Draft after their season ended with a win ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...