One of these hairpin loops contains a sequence called the anticodon, which can recognize and decode an mRNA codon. Each tRNA has its corresponding amino acid attached to its end. When a tRNA ...

The third base of a codon can form non-standard base pairs with the first base of the anticodon, allowing for more flexibility in codon recognition. Wobble base pairing enables a single tRNA molecule ...

The key structural features of tRNA include: The specificity of tRNA-amino acid interactions and the accuracy of codon-anticodon recognition ensure the faithful translation of the genetic code into ...

Although the pairing between codon and anticodon takes place over ... which is the 3' end of the tRNA, binds to its corresponding amino acid at an attachment site that is also three nucleotides ...

coli tRNA Lys triggered by phage-activation of a latent host-encoded anticodon nuclease PrrC ... element that accounts for guanine nucleotide specificity. Mutations of amino acids that contact the ...

the researchers identified 12 highly active tRNA synthetase/tRNA pairs in Escherichia coli that can add canonical and noncanonical amino acids. Then, Badran’s team used iterative rounds of genetic ...

When they treated the cultures with synthetic tRNA that carried an easily traceable unconventional amino acid and recognized these rare codons, they found that the TCG triplet introduced the new ...