They used two different types of lung cells: BEAS-2B cells, which represent normal lung-lining cells, and A549 cells, which come from lung cancer tissue and are commonly used in respiratory studies.

"The newly proposed MMA allowed the team to find a few key VOCs that could reliably separate lung cancer cells (A549) from normal lung cells (BEAS-2B)," said Dr. Ge Dianlong, a member of the team.

We employed the CRISPR/Cas9 genome editing platform for the generation of the desired targeted genomic rearrangement in the A549 lung cancer cell line. Single guide RNAs (sgRNAs) designed and ...

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which represent normal lung-lining cells, and A549 cells, which come from lung cancer tissue and are commonly used in respiratory studies. The researchers exposed these cells to different ...