∥ Laboratoire de Biochimie et Biophysique des Systèmes Intégrés (BBSI), Institut de Recherches en Technologies et Sciences du Vivant (iRTSV), UMR 5092 CNRS-CEA-UJF, Grenoble, France *To whom ...

Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Centre, Einthovenweg 20, 2333 ZC Leiden, The Netherlands ...

Structural analyses and mutation studies reveal that the NIS is essential for the ATPase reaction cycle and the two ... minus end disfavours both ADP release and ATP binding 50,51.