This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Terremoto Biosciences patents AKT1 inhibitors for cancer Feb. 26, 2025 Terremoto Biosciences Inc. has synthesized new 3 H -imidazo[4,5- b ]pyridine compounds acting as RAC-α serine/threonine-protein ...

Result: A total of 538 targets of GSP and 10795 DU-related targets were predicted; Venn analysis identified 215 potential targets for GSP to accelerate DU wound healing; PPI network analysis suggested ...

Forbes contributors publish independent expert analyses and insights. Asif Burhan is a freelance journalist who covers women's soccer.

Recent advances point to novel mechanisms by which the canonical Wnt signaling cascade in DCs regulates immune suppression, and the same pathway in tumors is associated with the evasion of anti-tumor ...

2019). In the present study, we describe a gradient-independent Wnt signaling in instructing stereotyped developmental neurite pruning of the PDB cholinergic motor neuron in C. elegans. From genetic ...

The inductive roles of FGF, Wnt, and BMP at the neural plate border are well established ... and neural crest defects in CAPE-treated embryos are suppressed by constitutively active Akt1. Inhibition ...