Through producing acetyl-CoA from acetate, ACSS2 epigenetically controls gene expression. However, whether and how ACSS2 regulates senescence remains unclear. Here, the authors link ACSS2 ...

Through the generated simulations, we have shown that KB concentration levels rise during prolonged starvation, and in consideration of glucose hypometabolism, MCT-induced intervention increases the ...

Here the authors show that the bacteria tap into disease tolerance by altering host cell acetyl-CoA metabolism to suppress innate cell function and cytokine production. ‘T cell engagers promote ...

Here, we examined the effect of different carbon sources that are involved in the major metabolic pathways of acetyl-CoA synthesis on myocardial infarction and found that elevation of acetyl-CoA by ...