What is exactly congenital adrenal hyperplasia and what are its causes ... while the outer section, the cortex, is responsible for releasing cortisol (the stress hormone), aldosterone (the ...

Classic congenital adrenal hyperplasia, more commonly called classic CAH, is when there is an enzyme missing in the adrenal gland, which causes the body to have the inability to make enough cortisol.

Chronic ACTH stimulation, as seen typically in untreated Cushing disease, leads to a nodular hyperplasia of the adrenal cortex. This finding suggests that a certain small population of ACTH ...