Drug reaction with eosinophilia and systemic symptoms ... is a likely contributor in some patients. Epoxide hydroxylase normally detoxifies the metabolites of aromatic amine anticonvulsant drugs such ...

Herein we report a new strategy for the synthesis of β-amino alcohols by reacting cardanol epoxide with diverse amines (aliphatic/aromatic) under catalyst-free and mild conditions in which ethanol is ...

Researchers from the National University of Singapore (NUS) have pioneered a new catalytic transformation that converts ...

Researchers have pioneered a new catalytic transformation that converts epoxides into fluorinated oxetanes, a coveted but difficult-to-make class of drug molecules that escaped synthetic preparation ...

Small, polar rings and electron-withdrawing atoms are both well-loved motifs in medicinal chemistry. So oxetanes and fluorine atoms could be a match made in drug discovery heaven. Researchers devised ...

The rumbling was felt up and down the New England coast, and while most reactions were of the “Did you feel that??” variety, there were also plenty of clever takes from Greater Boston ...

That is your lot for tonight. You don't have to wait long for more FA Cup action as Doncaster entertain Crystal Palace tomorrow. Thanks for joining us and for your comments. Enjoy the rest of your ...

pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. While performing a high-throughput screen (HTS) that identified ...

Smart citations by scite.ai include citation statements extracted from the full text of the citing article. The number of the statements may be higher than the number of citations provided by ACS ...