Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the ...

The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing ...

Research shows short-term fasting improves glucose regulation, while long-term fasting in young mice impairs β cell function, ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

Symlin (pramlintide) is an amylin analog used in conjunction with insulin ... However, in some cases, two other medical procedures are used: islet cell transplantation and whole pancreas ...

Plasma insulin, C-peptide, glucagon, (total) amylin, gastric inhibitory peptide (GIP), and ... and increases circulating plasma TAG concentration. Exposure of pancreatic beta-cells to excess fatty ...

Pancreatic cancer patients with high densities of CD8 + T cells in the juxtatumoural compartment have longer survival times. Cancer-associated fibroblasts within the stroma are able to attract and ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

Using a rat model of type-2 diabetes that expresses amyloid-forming human amylin in the pancreas (the HIP rat), we previously ... microvascular injury involve damage of the endothelial cell tight ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.