eLife19h
Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection
This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...
eLife19h
Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer
These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...
gut.bmj14h
Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn’s disease (ANDANTE I and II)
Effects of PF-04236921, an anti-IL-6 antibody, in adults with CD are reported ... Results from faecal calprotectin assays were highly variable at baseline and over time in all groups. No significant ...