The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...
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Nucleic acid drug iSN40 shows promise for osteoporosis treatmentExcessive osteoclast activity can lead to increased bone resorption, which contributes to osteoporosis. The findings revealed that iSN40 completely inhibits the differentiation of osteoclast ...
The structural integrity of bones has been attributed to bone remodeling—a highly regulated process of bone formation and bone resorption ... bones and eventually lead to detrimental health ...
Yamada et al. evaluated the performance of serum tartrate-resistant acid phosphatase 5b (TRACP5b), a biochemical marker for bone resorption, in comparison with established markers in the ...
as their low oestrogen levels can lead to increased bone resorption and accelerated bone loss. “Certainly we still need better drugs because none of the current drugs eliminate fractures.
and a lead author of the paper. Bone is constantly being remodeled through a process of resorption, in which old bone tissue is removed by osteoclasts, and formation, in which the old bone tissue ...
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) and a common cause for neurological disabilities in young adults. Although it is known that the peripheral ...
The structural integrity of bones has been attributed to bone remodeling—aa highly regulated process of bone formation and bone resorption ... bones and eventually lead to detrimental health ...
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