Higher concentrations have a greater effect on the pH than lower concentrations because there are more particles available to react with water and change the hydronium ion concentration. The purpose ...

In this installment, I primarily discuss considerations to keep in mind when choosing buffering additives that will be used ...

“The advantages are that you can run this purification entirely in a neutral pH buffer of your choice and remove problematic elution buffers. For instance, imagine replacing low pH buffers used ...