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A phase II trial of pembrolizumab plus platinum-based chemotherapy as first-line systemic therapy in advanced penile cancer: HERCULES (LACOG 0218) trial. JNJ-6420 exposure and clinical activity.

Figure 5: CD14 and TLR2 mediate activation of THP ... Studies with monoclonal antibodies known to be specific blockers of TLR2 or TLR4 showed that only TLR2 monoclonal antibodies block responses ...

Background We sought to identify an optimal oral corticosteroid regimen at the onset of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), which would delay time to first relapse ...

Timing and Outcomes of Palliative Care Integration Into Care of Adolescents and Young Adults With Advanced Cancer The advent of next-generation antibody-drug conjugates (ADCs), particularly ...

Alchemab, which is based in the U.K., seeks to develop antibody therapies for ALS and other conditions. Their approach involves analyzing antibodies that occur naturally in people who are resilient to ...

Engineering an antibody against flu with sticky staying power Aerosol treatment adheres to lung lining, blocks infection in mice Date: May 8, 2025 Source: Ohio State University Summary: Scientists ...

Scientists have made a potent antivenom using antibodies from a man who has been bitten hundreds of times by venomous snakes. The therapy protects mice against the venoms of 19 species of deadly ...

Department of Discovery & Development Technologies, The Healthcare Business of Merck KGaA, Darmstadt 64293, Germany ...

Stalk-targeting antibodies, like the one used in the study, have been found to protect against a wider variety of flu viruses than those that target less conserved parts, Mr. Reed explained.