Among the different isoforms of carbonic anhydrases ... Recent research has highlighted innovative approaches to designing carbonic anhydrase inhibitors, particularly those targeting CA IX ...

These inhibitors work by blocking the carbonic anhydrase enzyme family, particularly CA-II and CA-IV isoforms, which are crucial in maintaining ocular fluid balance. By interrupting the catalysis of ...

Carbonic acid is a heavy gas —it extinguishes fire and destroys all animal life. If an animal attempts to breathe it pure, there is spasmodic closure of the glottis and the animal dies as ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Biological nanopores offer a promising approach for single-molecule analysis of ...

Iron is an essential micronutrient for cell survival and growth; however, excess of this metal drives ferroptosis. Although maternal iron imbalance and placental hypoxia are independent contributors ...

Correction to: Fischer et al., Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance.

HIF-1α also regulates PI3K, VEGF, EPO, MKP-1, Glut-1, and many glycolytic enzymes, including glyceraldehyde 3-phosphate dehydrogenase, phosphoglycerate kinase 1, 12-lipoxygenase, proapoptotic members ...

The volumes of a cell [cell volume (CV)] and its organelles are adjusted by osmoregulatory processes. During pinocytosis, extracellular fluid volume equivalent to its CV is incorporated within an hour ...