Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

High CDC20 expression promotes aneuploid cancer cell sensitivity to spindle assembly checkpoint (SAC) inhibition by ...

Recently, I purchased a set of plates that looked like they were from the '70s, and I use them nearly every night. One evening while admiring the design, I began to wonder what year, exactly ...

Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

According to precedent and due to his status, Yoon will probably be assigned a solitary cell, likely bigger and better appointed than the standard 6.56 square metre (71 square feet) single cells.

Plants use silicon in their cell walls; some animals even use ... Like the carbon cycle and water cycle, plate tectonics are part of the biogeochemical cycles by which silicon, phosphorus, iron ...

This developmental plasticity requires a strict temporal and spatial control of the cell cycle. Cell-cycle activation in quiescent cells is correlated with a change in chromatin structure and ...

Battery cells work by chemical reactions, and the fascinating Hybrid Microbial Fuel Cell design by [Josh Starnes] is no different. True, batteries don’t normally contain life, but the process ...