Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single ...

The ability to obtain an accurate three-dimensional image of an intact cell is critical for unraveling the mysteries of cellular structure and function. However, for many years, tiny structures ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before ...

A new ultra-high resolution 'nanoscope' is capable of taking 3-D images of an entire cell and its cellular constituents in unprecedented detail, an advance that could reveal biological phenomena never ...

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells ...

Cells have their own tiny skeletons that are responsible for many important cellular functions. Scientists have developed novel fluorescent probes for imaging these important structures easily and ...

NIH researchers are working towards reducing cell-line development timescales to help tackle future pandemics.

By calculating the difference between the two images, a high-resolution, three-dimensional image of the tumour cells is created, which is free of the otherwise overwhelming background contrast.

With cell lines in hand that label 25 individual structures, the scientists then captured high-resolution, 3D images of more than 200,000 different cells.

For modern biotherapeutics, cell line development workflows must include more than just automated liquid handling.