TF (tissue factor) generated by damaged vessels and epithelial cells can lead to thrombin (IIa) generation by the extrinsic coagulation cascade. ADP and IIa can ... the promoter, the first exon and ...

17 Thus, we used, for the first time, a human LPS model to clarify ... The effects of aspirin and acetaminophen on activation of the coagulation cascade (reported here) and the release of circulating ...