Bacteriophages, the most abundant life form on Earth, infect bacterial cells and influence the structure of the microbial ...

Thus, viral ATP-dependent DNA ligases have an intrinsic nick-sensing function. Nick recognition by vaccinia DNA ligase and Chlorella virus DNA ligase also depends on occupancy of the AMP binding ...

This article was originally published with the title “ The Recognition of DNA in Bacteria ” in Scientific American Magazine Vol. 222 No. 1 (January 1970), p. 88 doi:10.1038 ...

A third advantage of EC sensors is their ability to achieve precise DNA recognition due to localization effects. Traditional detection methods, based on temperature or chemical control schemes ...

Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

Beyond revealing a secret to bacterial survival, the research has uncovered components that could be applied to gene editing: guide DNA, which is more stable and cheaper to synthesize than guide ...

Georgia State University researchers used simulations to study DNA repair mechanisms, focusing on the pre-incision complex in ...

Researchers from the Skoltech Laboratory for Metagenome Analysis, which is led by Assistant Professor Artem Isaev, and their colleagues from the United Kingdom have studied the BREX methyltransferase ...

In simple type II R-M systems, methylase and restrictase are two separate proteins, whereas in BREX, both the methylation of its own DNA and the recognition and restriction of unmethylated viral ...