A method for genetically barcoding Drosophila is developed and used to tag defined cell populations in vivo for single-cell transcriptomics experiments and to enable multiplexed behavioral analysis.

The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

The Midlands Integrative Biosciences Training Partnership is a BBSRC-funded doctoral training partnership between the universities of Warwick, Birmingham, Leicester, Aston, Harper Adams and Coventry.

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

Institute of Biophysics of the Czech Academy of Sciences, Kralovopolska 135, 612 00 Brno, Czech Republic ...

RNAi and miRNAs use related pathways to make ... only in the last two years have we built the connectome of the fruit fly (Drosophila melanogaster) and of a 1 cubic mm chunk of the human brain.

RNA isolation, cDNA synthesis, and RT-qPCR Total RNA was purified using Maxwell RSC simplyRNA Tissue kit (Promega, AS1340). The cDNA was synthesized from 3 μg of total RNA with a Transcriptor First ...