For the 10 questions on medications that can prolong the QT interval, the median number of correct answers for internists was 5 (interquartile range 3-7), for psychiatrists 5 (interquartile range ...

Pfizer Inc. today announced positive topline results from the progression-free survival (PFS) analysis of the Phase 3 BREAKWATER study of BRAFTOVI® (encorafenib) in combination with cetuximab ...

Pfizer Inc. (NYSE: PFE) today announced positive topline results from the progression-free survival (PFS) analysis of the Phase 3 BREAKWATER study of ...

Everyone is encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1 ...

Main outcome measures Maximal QTc interval prolongation and its relationship ... The simultaneous presence of several QT-prolonging factors (such as drugs, genetic predisposition, electrolyte ...

The advent of new drugs to treat tuberculosis and enhanced ... uncorrectable electrolyte disorders; a QT interval corrected according to Fridericia’s formula (QTcF) of at least 450 msec ...

Medically reviewed by Alex Yampolsky, PharmD Hydroxyzine, whose brand names include Atarax and Vistaril, and Benadryl, the ...

Brittney Hoffman, 31, picked up a new prescription last year to treat ADHD symptoms, but initially was confused about the ...

Background: This study examines the impact of Phα1β, a spider peptide derived from the venom of Phoneutria nigriventer, on the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG ...

All drugs can be expected to be effective against the majority ... Sotalol must be discontinued if prolongation of the QT interval is noted (corrected QT interval >0.5 s). The therapy will be judged ...

Likewise class 3 drugs (bretylium, amiodarone) also prolong the QT interval and may predispose to arrhythmias. The use of β blockers may further reduce myocardial contractility and although reported ...

The study aimed to assess the prevalence and characteristics of potential drug-drug interactions (pDDIs) that increase the risk of QT prolongation, in a population of cardiovascular disease patients.