Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, and ‡ Chromosome Engineering Research Center, Tottori University, 683-8503, ...

Contributed by Francisco Mauro Salzano, January 2, 2017 (sent for review July 5, 2016; reviewed by Theodore G. Schurr and Anne C. Stone) ...

a genetic disorder caused by duplications in the 15q11-q13 region, has been associated with autism spectrum disorder (ASD); however, research on chromosome 15 microduplications is scarce. We explored ...

Genome duplication is the process by which additional ... are polyploid – they contain more than two homologous sets of chromosomes. The diversity and genomic resources of Brassicaceae make ...

The objective of this study was to identify polyploid plants from citrus rootstocks and to evaluate the influence of the genetic constitution and of the environment on the frequency of chromosome ...

Human cells typically carry 46 chromosomes, including 22 pairs of non-sex chromosomes, numbered 1 through 22, and one pair of sex chromosomes. Each parent contributes one-half of each pair of non ...

A baby born with a rare and devastating genetic condition has become the first person ever to be successfully treated with a personalized CRISPR therapy. After receiving three doses of the therapy ...

About 5% of patients with autism have a chromosome abnormality visible with cytogenetic methods. The most frequent are 15q11–q13 duplication, 2q37 and 22q13.3 deletions. Many other chromosomal ...

We thank Unique-The Rare Chromosome Disorder Support Group, a UK-registered charity and the online US-based 15q11.2 duplication network group for advertising the study and for referred participants.

Once the fcfDNA is separated, the ratio of genetic information can be sampled and compared between different chromosomes to detect aneuploidies, 29 and in the future, clinical testing could also be ...

The Angelman syndrome (AS) (developmental delay, mental retardation, speech impairment, ataxia, outbursts of laughter, seizures) can result either from a 15q11-q13 deletion ... with the markers ...